Objective: The present research was conducted with the aim of determining the strategies of using the Instagram social network for the development of personal branding and career success.Methods: The present research was conducted with a mixed method. In the qualitative part, an in-depth interview was conducted with 17 experts in the field of branding. Data analysis has been done by grand theory method, the quantitative part has been done by using the researcher-made questionnaire tool, 392 people from the field of personal branding in the Instagram social network have been selected and asked for opinions.Results: The research findings are presented in the qualitative section with 120 primary codes and 28 subcategories, the strategies of using the Instagram social network in personal and professional branding in 5 subcategories (brand development, reaching a wide audience, ease of communicating and interacting with audiences, lack of The space and time limitations for developing experiences and business) were explained. The indicators of the use of Instagram in personal and professional branding were identified in the form of 6 subcategories (content marketing, the possibility of validation, the use of personalities, and the possibility of republishing content), the platforms and infrastructures of the use of Instagram in personal and professional branding in the form of 3 subcategories (necessary providing legal infrastructure, hardware and software equipment and facilities) were categorized. Obstacles and disturbing factors in the use of Instagram in personal and business branding were organized under 4 subcategories (unsuitable infrastructure, security threats, lack of payment gateways and lack of legal protection). Also, appropriate strategies for using the Instagram social network in personal and professional branding were presented in the form of 6 sub-categories (use of communication and information capacities of virtual space, brand management practices, audience-oriented, identity building and creativity) and at the end of the results The use of Instagram social network in personal and professional branding was presented and explained in the form of 4 sub-categories (establishing and introducing the brand, business development, improving relations with customers). In the quantitative part, 392 activists and owners in the field of personal and professional branding in the Instagram social network were studied using a closed questionnaire. The findings of the quantitative section showed that there is a significant relationship between the variable of Instagram social networks with personal branding and career success with path coefficients of 0.895, 0.647 and 0.250 respectively. Also, personal competencies with a path coefficient of 0.326 and 0.215, respectively, have a significant effect with the variables of personal branding and career success, and personal branding with a path coefficient of 0.525 has a significant effect on career success. Also, the mediating role of individual competencies and personal branding and career success in relation to Instagram social networks was confirmed. There is a significant relationship between Instagram variable with personal branding and career success with path coefficients of 0.895, 0.647 and 0.250 respectively. Also, the mediating role of personal competencies and personal branding and career success in relation to Instagram was confirmed.Conclusions: The results of this research in both qualitative and quantitative parts showed that the use of the Instagram social network plays an important and influential role for the development of personal branding and career success, especially in the field of internet businesses, considering its capabilities and functions.Keywords: strategies, Instagram, personal branding, career success.